Tests

PCI offers the following specialist assays including interpretation and reporting with MDT support if required:

Breast

• PD-L1 IHC for TNBC
• Her-2 IHC (alone or inclusive of reflex DDISH)
• Her-2 DDISH
• ER & PR IHC (alone or in combination)
• ER, PR & Her-2 IHC (alone or inclusive of reflex DDISH)

Non small cell lung cancer

• ALK IHC
• PD-L1 IHC
• ROS-1 IHC
• BRAFV600E IHC
• EGFR PCR
• BRAF PCR

All the above can be packaged together for a 48h TAT
FISH for ALK or ROS-1 has additional cost

Colorectal cancer

• KRAS PCR
• BRAF PCR
• NRAS PCR
• MMR IHC (alone or inclusive of BRAFV600E IHC)
• BRAFV600E IHC
• Her-2 IHC (and DDISH)
• PTEN (IHC)

All the above can be packaged together for a 48h TAT

Melanoma

• BRAFV600E IHC
• BRAF PCR
• NRAS PCR
• PD-L1 IHC
• BAP-1 IHC
• PRAME IHC

Other

• PD-L1 IHC for mUC or other indications
• MMR IHC (alone or inclusive of BRAFV600E IHC)
• BRAFV600E IHC for thyroid or other cancer sites
• p16INK4A IHC
• Basal cell cocktail (34BE12, p63, P504s) multiplex IHC for prostate biopsies
• ERG/PTEN multiplex IHC for prostate cancer
• p16INK4A/Ki-67 multiplex IHC for cervical biopsies

Guide Prices per Test

ER, PR, Her2		£100
PD-L1, EGFR, ALK-1, BRAF, ROS-1		£600
MSH-6, MSH-2, MLH-1, PMS-2, BRAF		£180
KRAS, BRAF, NRAS, MMR		£460
Rapid BRAF for melanoma (if negative, it requires PCR for BRAF and NRAS)		£90 £170
PD-L1 SP142 or SP263		£175
IHC		£20-£45
ISH		£170
Multiplex IHC		P.O.A.

Wet tissue to diagnosis:
	small biopsies		£70 - £150
	large non-cancer		£120 - £250
	large cancer		£300 - £500
Reporting only:
	small biopsies		£35 - £50
	large non-cancer		£60 - £150
	large cancer		£120 - £250

Many of these tests have been arranged into commonly used panels with an associated reduction in cost.
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PCI welcomes enquiries to discuss your exact requirements using the following contact details:
 admin@poundburycancerinstitute.org